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migraine, and a class of dopamine agonists used in the treatment of Parkinson disease has ergot activity Chronic overdosage of the drug is the usual cause of ergotism; acute overdosage in the postpartum state or in the treatment of migraine may cause an alarming rise in blood pressure Two types of ergotism are recognized: gangrenous, due to a vasospastic, occlusive process in the small arteries of the extremities, and convulsive, or neurogenic ergotism The latter is characterized by fasciculations, myoclonus, and spasms of muscles, followed by seizures In nonfatal cases, a tabes-like neurologic syndrome may develop, with loss of knee and ankle jerks, ataxia, and impairment of deep and super cial sensation The pathologic changes are said to consist of degeneration of the posterior columns, dorsal roots, and peripheral nerves, but they have been poorly described The relation of these changes to ergot poisoning is not clear, since most of the cases have occurred in areas where malnutrition was endemic The authors have had no experience with this condition asp net mvc 5 pdf viewer How to display generated PDF file in a new browser tab | ASP.NET ...
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Apr 8, 2017 · how to create pdf in aspnet mvc using itextsharpdll generate pdf from any html it is simple. Ingestion of marine toxins that block neural sodium channels is a common form of poisoning throughout coastal areas and islands of the world It results from eating sh that have fed on toxin-containing microscopic dino agelates Reef sh and shell sh are exposed to high concentrations of these organisms during periodic upswings in the population of the dino agelates They may be so profuse as to color the surrounding water (red tide) Although the toxins differ (tetrodotoxin puffer sh; ciguatoxin snails; saxitoxin and brevitoxin shell sh), the neurologic and gastrointestinal symptoms that follow the ingestion of poisoned sh are similar The initial symptoms are diarrhea, vomiting, or abdominal cramps coming on minutes to hours after the ingestion These are followed by paresthesias that begin periorally and then involve the limbs distally Hot and cold sensory stimuli (eg, ice cream) are characteristically associated with electrical-like or burning paresthesias Muscle aches and shooting pains are also mentioned by most patients In puffer sh poisoning and in advanced stages of poisoning from other sh, weakness occurs, and there have been a few reports of coma and of respiratory failure The recognition of this type of sh poisoning is straightforward in endemic areas, in some of which there is a seasonal clustering of cases In tourists returning home from endemic areas or in persons consuming imported sh, the illness may be mistaken for the Guillain-Barre syndrome Prom inent perioral paresthesias should suggest the correct diagnosis Supportive treatment is all that is required, but treatment with intravenous mannitol is said to hasten recovery Pearn reviews the biochemistry and physiologic and clinical effects of the various marine toxins and points out a form of chronic intoxication unknown to us but apparently endemic in certain island communities The ostensible main chronic effects are severe fatigue and asthenic weakness The problem of distinguishing this syndrome from depression is acknowledged by the author and the cases on which we have consulted locally almost always fall into the psychiatric category. Lathyrism is a neurologic syndrome characterized by the relatively acute onset of pain, paresthesias, and weakness in the lower extremities, progressing to a permanent spastic paraplegia It is a serious medical problem in India and in some North African countries and is probably due to a toxin contained in the chickling vetch, Lathyrus, a legume that is consumed in excess quantities during periods of famine This disorder is discussed further with the spinal cord diseases (page 1083) asp.net mvc pdf to image Create and Print PDF in ASP . NET MVC | DotNetCurry
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